<ruby id="zbzzx"><b id="zbzzx"></b></ruby>
<pre id="zbzzx"><ruby id="zbzzx"><mark id="zbzzx"></mark></ruby></pre>

    Recombinant Mouse BCMA/TNFRSF17 (hFc Tag)

    更多活動更多優惠,盡在翌圣商城》

    批量采購, 請點擊詢價

    產品說明書

    FAQ

    COA

    已發表文獻

    產品信息

     

    產品名稱

    產品編號

    規格

    價格(元)

    Recombinant Mouse BCMA/TNFRSF17 (hFc Tag)

    93112ES25

    25 μg

    1185

    93112ES60

    100 μg

    3665

    93112ES76

    500 μg

    13255

    93112ES80

    1 mg

    23295

     

    產品描述

     

    BCMA, B cell maturation antigen, is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development, function and regulation. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity.  

     

    產品性質

     

    別名

    CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

    Uniprot No.

    O88472.1

    表達區間及表達系統

    Recombinant Mouse BCMA/TNFRSF17 Protein is expressed from HEK293 Cells with hFc tag at the C-terminal. It contains Met1-Thr49.

    分子量

    Approximately 31 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.

    純度

    > 95% as determined by SDS-PAGE and HPLC.

    活性

    SPR Data: Human BAFF Trimer, His-Flag Tag captured on CM5 Chip via Anti-His Antibody can bind Mouse BCMA, hFc Tag with an affinity constant of 2.68 nM as determined in SPR assay (Biacore T200).

    內毒素

    1.0 EU per 1μg of the protein by the LAL method.

    制劑

    Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

    復溶

    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

     

    運輸與保存方法

     

    冰袋運輸。-20-80存,一年有效期。

    復溶后,-20 -80°C,在未開封狀態下保存 3-6 個月。復溶后,2-8°C 保存 2-7 天。

    建議第一次使用時分裝存,避免反復凍融。


     注意事項

     

    1. 避免反復凍融。

    2. 為了您的安全和健康,請穿實驗服并戴一次性手套操作。

    3. 本產品僅作科研用途!

     

    產品數據

    image.png
    image.png

    HB220805


     

    400-6111-883

    亚洲国产欧美日本精品,网站免费观看国产精品,国产午夜精品久久精品电影_观看