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    Recombinant Human CD38 (hFc Tag)

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    產品信息

     

    產品名稱

    產品編號

    規格

    價格(元)

    Recombinant Human CD38 (hFc Tag)

    93115ES25

    25 μg

    1695

    93115ES60

    100 μg

    3885

    93115ES76

    500 μg

    12255

    93115ES80

    1 mg

    21385

     

    產品描述

     

    CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

     

    產品性質

     

    別名

    ADPRC 1; T10; CD38; ADP-ribosyl cyclase 1; cADPr hydrolase 1; CD38 molecule; EC 2.4.99.20; EC 3.2.2.6

    Uniprot No.

    P28907.1

    表達區間及表達系統

    Recombinant Human CD38 Protein is expressed from HEK293 Cells with hFc tag at the C-terminal. It contains Val43-Ile300.

    分子量

    Approximately 56.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

    純度

    > 95% as determined by SDS-PAGE and HPLC.

    活性

    ELISA Data: Immobilized Human CD38, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CD38 Antibody, hFc Tag with the EC50 of 17.4ng/ml determined by ELISA.

    內毒素

    1.0 EU per 1μg of the protein by the LAL method.

    制劑

    Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

    復溶

    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

     

    運輸與保存方法

     

    冰袋運輸。-20-80存,一年有效期。

    復溶后,-20 -80°C,在未開封狀態下保存 3-6 個月。復溶后,2-8°C 保存 2-7 天。

    建議第一次使用時分裝存,避免反復凍融。

     
    注意事項

     

    1. 避免反復凍融。

    2. 為了您的安全和健康,請穿實驗服并戴一次性手套操作。

    3. 本產品僅作科研用途!


    產品數據


    image.png

    HB220808



    400-6111-883

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